Presented by the Center for Genomic Science Innovation
Fall 2021
UW Carbone Cancer Center is piloting a new front-door patient consent process that will make genomic and clinical data more readily available to UW researchers for broad translational advances.
Six summer undergrads in the Biomedical Data Science Summer Research Opportunity Program overcame pandemic restrictions through a unique team-science research experience.
Having trained at UW-Madison, Dr. Jessica Lang simply couldn’t stay away.  She returns as an Assistant Professor with deep expertise in chromatin dysfunction in ovarian and other cancers.
A National Human Genome Research Institute (NHGRI) grant awarded to UW Madison is one of 25 awards made to institutions as part of a flagship consortium to understand human genomic variation.
News and Events
Genomics Seminars
1:30 pm first Thursday of the month

  • Oct 7, Hilary Finucane, Broad and Harvard, Insights from complex trait fine- mapping in diverse populations 
  • Nov 4, Megan McClean, UW-Madison, Single-cell measurement and control to unravel signaling heterogeneity in yeast 
  • Dec 2, Anna Gloyn, Stanford University, Drilling down on mechanisms for islet cell dysfunction in diabetes: Mining Type 2 Diabetes GWAS for Gold 

12 pm Mondays monthly   

  • Sept 20, Wendy Chung, Colombia University, “Genomic Medicine: Opportunities and Challenges” 
  • Oct 18, Valentina Lo Sardo, UW-Madison, TBD 
  • Nov 15, Gaelen Hess, UW-Madison, TBD

Seminars around campus: 
  • Sept 30, 3:30 pm, Biology Colloquium:  Prashant Sharma UW Madison), "Analyses of genome architecture and comparative development break century-old impasses in the biology of 'Arachnida'” 
  • Oct 8, 12 pm, BMI Seminar Series:  Itai Yanai, New York U.  “Decoding developmental gene pathways with single-cell transcriptomics” 
  • Oct 15, 12 pm, BMI Seminar Series:  Sara Mostafavi, U. Washington, Deep Learning methods applied to multi-omic data. 
  • Oct 22, 12 pm, BMI Seminar Series:  Alexis Battle, Johns Hopkins.  Unlocking the secrets of the human genome. 
  • Oct 27, 3:30 pm, Genetics Colloquium:  Elise Robinson, Broad Institute, TBD. 
  • Oct 29, 12 pm, BMI Seminar Series:  Elana Fertig, Johns Hopkins, TBD. 
  • Oct 28, 12:30 pm, Evolution Series:  Stephany Virrueta Herrera ( Early Career Grad Student Awardee), University of Illinois at Urbana- Champaign,  “Using genomics to uncover the evolutionary histories of ectoparasites on birds and mammals” 
  • Nov 18, 12:30 pm, Evolution Series:  Aaron Ragsdale, UW-Madison- Integrative Biology, “Inferring population structure in early human history.” 
  • Nov 19, 12 pm, BMI Seminar Series: Jomol Mathew, UW-Madison, SMPH Chief Biomedical Informatics officer, TBD 
  • Nov 22, 3 pm, Biochemistry Colloquium: Vatsan Raman, UW-Madison  “Deciphering the Molecular Code of Bacteriophage-host Interactions by Deep Mutational Scanning” 

Oct 8, UW-Madison Epigenetics Symposium

  • Register for the upcoming 5th Annual UW Epigenetics Symposium, Friday, Oct. 8th at the Wisconsin Institute for Discovery! Come and learn about the new and exciting discoveries in chromatin/epigenetics happening on our campus. There will be presentations from our keynote speaker, Dr. Ting Wang from Washington University in St. Louis (here), UW epigenetic researchers, a poster session by trainees, and a reception to wrap up the day. Labs are encouraged to submit 1 to 2 posters. From these poster abstracts, a number of 2-3 minute talks from trainees will be selected. 
  • Please click here to register by Wednesday, September 22nd. 
Oct 21-24, Wisconsin Science Festival
Courses & Workshops

Next Gen. Data Analysis Workshops at the UW Biotechnology Center/Bioinformatics Resource Core 

UW Libraries Graduate Support workshop series 

Technology Updates 

UWBC Oxford Nanopore Technologies Update
The facility is now providing ultra-long sequencing services on the GridION and PromethION using the Ultra-Long DNA Sequencing Kit from Oxford Nanopore and Circulomics. This exciting technology increases sequencing output with read length N50 of 50-100+ kb, where previously output has suffered as a result of increased DNA fragment length.  This service will enable researchers to investigate large structural variants, perform haplotype phasing, and increase genome assembly contiguity. For more information, watch the Bio-Tech Talk given by Dr. Kelvin Liu, Founder and CEO of Circulomics or contact the facility.  

UWBC Illumina Update  
Illumina NovaSeq 6000 sequencing service costs have been reduced as of May 1, 2021. The NovaSeq 6000 is a high-throughput system capable of generating 3 trillion bases per day. The system is ideal for whole genome sequencing, Genotyping By Sequencing (GBS), RNA-Seq, 10x Single-Cell, ChIP-Seq, ATAC-Seq, and countless other applications. The facility’s novel Shared NovaSeq 6000 service allows researchers to leverage the throughput of the system without having to pay for an entire lane – ideal for small projects.  

UWBC PacBio Update  
We are pleased to announce the arrival of a second PacBio Sequel II. This additional instrument will improve PacBio turnaround times on your HiFi data. Inquire with the DNA Seq Facility to get your HiFi project started!