Presented by the Center for Genomic Science Innovation
Summer 2024
New UW faculty uses genomics and computation to investigate neurodegenerative diseases.
New UW faculty uses genomics and computation to investigate neurodegenerative diseases.
Dr. Kirstan Gimse explains her research on gene editing treatments for Alzheimer’s disease and the computational analysis behind it.
 
  • CGSI and Genetics faculty Chris Hittinger led a landmark study on genome evolution, offering a possible answer to one of the oldest questions in the field: why some species are generalists and others specialists.
  • Yury Bukhman and colleagues in the group of Ron Stewart at the Morgridge Institute published the reference genomes for the blue whale and the Etruscan shrew. 
  • CGSI and Biochemistry faculty Vatsan Raman and colleagues bring insight into the evolutionary rules of genetic regulation with protein ruggedness.  
  • Brad Schwab, from CGSI affiliate John Yin's lab, used computational models to predict viral fitness. 
  • A Research Forward grant that includes CGSI affiliate Jason Peters in the School of Pharmacy will incorporate transposon and CRISPR screening to investigate infectious disease therapies.  
 
Publication Highlights
  • Katsumura et al. (in CGSI affiliate faculty Emery Bresnick's lab) in PNAS describes how genetic variation in GATA2 creates a predisposition to bone marrow failure, which often precedes leukemia.
  • Gelman et al. (with CGSI affiliate Anthony Gitter's and Phil Romero's labs) proposes a new machine learning method for protein engineering that integrates biophysical modeling.
  • Gibson et al. (in CGSI affiliate Melissa Harrison's lab) in Nature Structural & Molecular Biology describes new insights on regulation of pioneer factor binding and function.
Full list of recent UW genomics publications
 

Thank you for your support during Day of the Badger!

CGSI joined the Day of the Badger for the first time! All the money raised will be used to train the next generation of genomics leaders in the Summer Research Opportunity Program in Genomic Data Science. 
You can still give to support students!
 
Awards and Congratulations
Congratulations to colleagues on their awards:
  • CGSI member Sündüz Keleş, Departments of Statistics & Biostatistics and Medical Informatics, received the 2023 SMPH Group of Women in Medicine and Science Impact award.
  • CGSI member Christina Kendziorski, Department of Biostatistics and Medical Informatics, was named Fellow of the Institute of Mathematical Statistics.
  • CGSI director Audrey Gasch, Laboratory of Genetics, was awarded a UW-Madison Kellett Mid-Career Award. 
  • CGSI affiliate Jean Michel-Ané, Departments of Bacteriology & Plant and Agroecosystem Sciences, was elected into AAAS.
  • CGSI affiliates Jean-Michel Ané, Departments of Bacteriology & Plant and Agroecosystem Sciences, and Guilherme Rosa, Department of Animal and Dairy Sciences, were awarded the Vilas Distinguished Achievement Professorship.
  • CGSI affiliate Jake Brunkard, Laboratory of Genetics, received a Vilas Faculty Early-Career Investigator Award.
  • Tyler Gibson from the Harrison Lab, Department of Biomolecular Chemistry, received a 2023 Raymond L. Erikson Exceptional Thesis Award.
Congratulations to CGSI lab undergraduates on recent awards: 
  • Hilldale Undergraduate/Faculty Research Fellowship: Katarina Aranguiz (Hittinger Lab), Sydney Olson (Lang Lab), Anna Sabel (Lo Sardo Lab), David Givand (Saha Lab), and Nikhil Chandra (Saha Lab). 
  • Sophomore Research Fellowship: Elizaveta Korolev (Hittinger Lab), Claire Schleicher (Raman Lab), and Meghan Basil (Suen Lab). 
News and Events
Genomics Seminars
CGSI Genomics Seminar Series
1:30 PM first Thursday of the month

  • Sep. 5, Barak Cohen, Washington University in St. Louis, "Integration of cis-regulatory information in the genome" 
  • Oct. 3, Kyle Gaulton, University of California San Diego, mapping gene regulation of type 1 diabetes and other complex diseases, title pending 
  • Nov. 7, Hee-Sun Han, University of Illinois Urbana-Champaign, "Comparative whole-brain spatial omics: Molecular annotation of neuronal circuitry"
  • Dec. 5, Brian Davis, Texas A&M University, "Pangenomes in canine and equine, the next evolution of comparative genomics"

Events
MERSCOPE Spatial Transcriptomics Seminar, Ziemann B (8th Floor of the Waisman Center), Jun. 21,  2:30-3:30 PM

2024 Wisconsin Human Proteomics Symposium – New Frontiers in Clinical Proteomics, UW-Madison, Jul. 31-Aug. 1
  • Register here
2024 Molecular Genetics of Bacteria and Phages Meeting, Madison, WI, Aug. 5-9

Genomics Data Carpentry, online,
Aug. 5-9 and Aug. 12-13, 9 AM-12:30 PM

RECOMB/ISCB Conference on Regulatory & Systems Genomics with DREAM Challenges, Madison, WI, Oct. 1-3
  • Presenter registration deadline: Sep. 10
  • Non-presenting participants registration deadline: Oct. 2
Advancing Precision Medicine Symposium, UW-Madison, Oct. 8
Fall Genomic Courses
AN SCI 366 – Concepts in Genomics, Francisco Peñagaricano 

Genetics 565 – Human Genetics, Donna Werling and Steven Schrodi 

BMI/COMP SCI 576 – Introduction to Bioinformatics, Colin Dewey 

ONC 675 – Mining Genomics Data, Huy Dinh 

CHEM 725 – Separations in Chemical Analysis, Lloyd Smith

BIOCHEM 729 section 8 – Responsible Conduct of Research, David C. Schwartz

BMI 775 – Computational Network Biology, Sushmita Roy and Anthony Gitter

BME 780 – Methods in Quantitative Biology, Megan McClean and Pamela Kreeger

Genetics 885 – Advanced Genomic and Proteomic Analysis, Nicole Perna and Audrey Gasch

CHEM 923 – Genomic Sciences Program Seminar, David C. Schwartz

Zoology 957 – Genomics of Polygenic Adapt'n, Carol Lee 

PATH 970 – Genomics, Proteomics, and Metabolomics: A Deep Dive into Omics Data Analysis, Thomas Raife
Full Genomic Course List
Have news or publications for G&T? Click here
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